Bringing a human element to chimeric mouse models.

 

The Hu-M™ IT Model

The only commercially available small animal model that allows testing of inflammatory or other human immune responses by monoclonal antibodies/small molecules/ anti-inflammatory compounds.

Applications

  • Novel immune-therapies (prediction of cytokine storm and lymphotoxicity from humanized monoclonal antibodies)

Advantages over existing models

  • Only pre-clinical small animal model allows for the prediction of cytokine release syndrome and/or potential lymphotoxicity from novel therapeutics. Cheaper and more relevant than alternate non-human primate (e.g Cyno monkey models)